Definition: Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.
Other names Immune-Response Antigens, Human; Immune-Associated Antigens, Human; Immune Response-Associated Antigens, Human; Ia-Like Antigens, Human; Human Class II Antigens; HLA-Dw Antigens; Class II Human Antigens; Antigens, HLA-D; Immune Response Antigens, Human; Immune Associated Antigens, Human; Ia Like Antigens, Human; Human Immune-Response Antigens; Human Immune-Associated Antigens; Human Ia-Like Antigens; HLA Dw Antigens; HLA D Antigens; Antigens, Human Immune-Response; Antigens, Human Immune-Associated; Antigens, Human Ia-Like; Antigens, HLA-Dw
