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Ibotenic Acid

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Definition: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.     
Pharmacological Action Excitatory Amino Acid Agonists 		Other names Acid, Ibotenic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-hydroxy-4,5,6,7-tetrahydroisoxazolo(4,5-c)pyridine-6-carboxylic acid  105701-67-5   Ibotenic Acid/*analogs & derivatives. Acta Chem Scand [B] 1986;40(2):92
3-hydroxy-4,5,6,7-tetrahydro-isoxazolo(4,5-c)pyridine-4-carboxylic acid  105701-66-4   Ibotenic Acid/*analogs & derivatives. Acta Chem Scand [B] 1986;40(2):92
4-bromohomoibotenic acid  121313-14-2   Ibotenic Acid/*analogs & derivatives. Nature 1980;284(5751);64
4-methylhomoibotenic acid  0   Ibotenic Acid/*analogs & derivatives. Nature 1980;284(5751):64
homoibotenic acid  71366-28-4 5-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-3-oxo-, (+-)  Ibotenic Acid/*analogs & derivatives. Nature 1980;284(5751):64
alpha-amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid  77006-27-0 4-Isoxazoleacetic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-, (+-)  Ibotenic Acid/*analogs & derivatives. Nature 1980;284(5751):64
4-methylibotenic acid  0   Ibotenic Acid/*analogs & derivatives. Nature 1980;284(5751):64

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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