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Lactoferrin

More information in Books or onNLM PubMed
Definition: An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the type III secretion system used by bacteria to export virulence proteins for host cell invasion.     
Pharmacological Action Anti-Infective Agents
Other names Lactotransferrin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PXL01 peptide  0   *Lactoferrin. J Hand Surg Eur Vol. 2011 Oct;36(8):656-62
lactoferrampin (268-284)  0   *Lactoferrin *Peptide Fragments. J Appl Microbiol 2010 Oct;109(4):1311-8
lactoferricin (17-30)  0   *Lactoferrin *Peptide Fragments. J Appl Microbiol 2010 Oct;109(4):1311-8
Ltf protein, mouse  0   *Lactoferrin.
talactoferrin alfa  0   *Lactoferrin Recombinant Proteins. Invest New Drugs 2006 May;24(3):233-40
LFampin 265-284  0   *Lactoferrin *Peptide Fragments. Peptides 2005 Nov;26(11):2093-7
lactoferrin-DTPA-Eu conjugate  0   *Lactoferrin Pentetic Acid/*analogs & derivatives Europium. Anal Biochem 2005 Apr 15;339(2):206-15
lactoferrampin  0   *Lactoferrin *Peptide Fragments. Biol Chem 2005 Feb;386(2):137-42
hololactoferrin, human  0   *Lactoferrin. J Vasc Res 2004 Jul-Aug;41(4):293-304
LTF protein, human  0   *Lactoferrin.
lactoferrin (1-11), human  0   *Lactoferrin *Peptide Fragments. Antimicrob Agents Chemother 2002 Jun;46(6):1634-9
Lfpep peptide  0   *Lactoferrin. FEBS Lett 1999 Dec 3;462(3):273-7
Boc-Lys(Boc)-Arg-Asp-Ser(tBu)-OtBu  0   *Lactoferrin *Peptide Fragments. Inflamm Res 1999 Sep;48(9):479-84
LBPA protein, Neisseria meningitidis  0   *Bacterial Outer Membrane Proteins *Receptors, Cell Surface Lactoferrin. Infect Immun 1995 Aug;63(8):2958-67
human lactoferrin peptide 2  0   *Lactoferrin *Peptide Fragments Anti-Bacterial Agents. FEBS Lett 1996 Mar 11;382(1-2):175-8
HLP1 protein, synthetic  0   *Lactoferrin *Peptide Fragments. FEBS Lett 1996 Mar 11;382(1-2):175-8
lactoferricin B  146897-68-9 L-Phenylalanine, L-phenylalanyl-L-lysyl-L-cysteinyl-L-arginyl-L-arginyl-L-tryptophyl-L-glutaminyl-L-tryptophyl-L-arginyl-L-methionyl-L-lysyl-L-lysyl-L-leucylglycyl-L-alanyl-L-prolyl-L-seryl-L-isoleucyl-L-threonyl-L-cysteinyl-L-valyl-L-arginyl-L-arginyl-L  *Lactoferrin.
Pharma Action Anti-Bacterial Agents ; Antifungal Agents ; Antiprotozoal Agents
Med Microbiol Immunol (Berl) 1993 May;182(2):97-105
lactoferroxin-C  117667-27-3   *Lactoferrin *Peptide Fragments. Agric Biol Chem 1990;54(7):1803
lactoferroxin-B  117667-26-2   *Lactoferrin *Peptide Fragments. Agric Biol Chem 1990;54(7):1803
lactoferroxin-A  117667-25-1   *Lactoferrin *Peptide Fragments. Agric Biol Chem 1990;54(7):1803
KRDS peptide  116430-80-9   *Lactoferrin *Peptide Fragments. Blood 1988;72(1):172
apolactoferrin  0   *Apoproteins *Lactoferrin. Biochim Biophys Acta 1983;759(3):229
lactoferrin receptors  0   *Receptors, Cell Surface Lactoferrin. Br J Haematol 1983;54(3):383

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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