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Lipoproteins, VLDL

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Definition: A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.  hypoprebetalipoproteinemia   
Examples Cholesterol, VLDL 		Other names Very-Low-Density Lipoproteins; Prebeta-Lipoproteins; Very Low Density Lipoproteins; VLDL3 Lipoproteins; VLDL2 Lipoproteins; VLDL1 Lipoproteins; VLDL Lipoproteins; Prebeta Lipoproteins; Pre beta Lipoproteins; Lipoproteins, Very-Low-Density; Pre-beta-Lipoproteins; Lipoproteins, VLDL3; Lipoproteins, VLDL2; Lipoproteins, VLDL1; Lipoproteins, VLDL III; Lipoproteins, VLDL I; Lipoprotein VLDL II
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
very low density lipoprotein receptor type II, human  0   *Receptors, LDL Lipoproteins, VLDL. Life Sci 2009 Mar 27;84(13-14):402-8
oxidized very low density lipoprotein  0   *Lipoproteins, VLDL Oxidation-Reduction. Chung Hua Ping Li Hsueh Tsa Chih 1996 Aug;25(4):220-3
glycosylated lipoproteins, VLDL  0   *Lipoproteins, VLDL Glycosylation. Monogr Atheroscler 1985;13:130
VLDL receptor  0   *Receptors, LDL Lipoproteins, VLDL. J Lipid Res 1982;23(7):984
very low density lipoprotein triglyceride  0   *Lipoproteins, VLDL *Triglycerides. Metabolism 1981;30(6):583
apolipoprotein VLDL II  0   *Apolipoproteins *Lipoproteins, VLDL. J Biol Chem 1980;255(21):10060

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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