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Lysergic Acid Diethylamide

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Definition: Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.  DF: note short X ref   
Pharmacological Action Hallucinogens; Serotonin Antagonists; Serotonin Receptor Agonists 		Other names Lysergide; LSD; LSD 25; Diethylamide, Lysergic Acid; Acid Diethylamide, Lysergic; Lysergic Acid Diethylamide Tartrate; LSD-25
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-desmethylnorlysergic acid diethylamide  0   Lysergic Acid Diethylamide/*analogs & derivatives. Clin Chem 2002 Sep;48(9):1615-8
2-oxo-3-hydroxylysergic acid diethylamide  0   Lysergic Acid Diethylamide/*analogs & derivatives. Acta Clin Belg Suppl 1999;1:94-6
LEK 8804  153415-44-2 Ergoline-8-carboxamide, 9,10-didehydro-6-methyl-N-(2-propynyl)-, (8beta)  Lysergic Acid Diethylamide/*analogs & derivatives. Pharmacol Biochem Behav 1994 Feb;47(2):301-5
2-bromolysergic acid diethylamide  478-84-2 Ergoline-8-carboxamide, 2-bromo-9,10-didehydro-N,N-diethyl-6-methyl-, (8beta)  Lysergic Acid Diethylamide/*analogs & derivatives.
N,N-diacetoxyethyl 9,10-dihydrolysergic acid amide  109002-91-7 Ergoline-8-carboxamide, N,N-bis(2-(acetyloxy)ethyl)-6-methyl-, (8beta)  Lysergic Acid Diethylamide/*analogs & derivatives. Pharmazie 1992 Feb;47(2):137-9
2-butyllysergamide  137765-82-3   Lysergic Acid Diethylamide/*analogs & derivatives. J Med Chem 1992;35(2):203
N-demethyllysergic acid diethylamide  35779-43-2   Lysergic Acid Diethylamide/*analogs & derivatives. Anal Chem 1988;60(14):1420
N(1)-methyl-2-bromo-lysergic acid diethylamide  50484-98-5   Lysergic Acid Diethylamide/*analogs & derivatives. Synapse 1987;1(5):393
N(1)-methyl-2-lysergic acid diethylamide  4238-85-1   Lysergic Acid Diethylamide/*analogs & derivatives. Mol Pharmacol 1986;29(2):120
N(1)-methyl-2-iodo-lysergic acid diethylamide  97165-34-9   Lysergic Acid Diethylamide/*analogs & derivatives Iodine Radioisotopes. Eur J Pharmacol 1985;110(1):147
lysergic acid alpha-hydroxyethylamide  3343-15-5   Lysergic Acid Diethylamide/*analogs & derivatives. Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao 1983;5(4):259
2-iodolysergic acid diethylamide  3712-25-2   Lysergic Acid Diethylamide/*analogs & derivatives. J Biol Chem 1983;258(20):12499
1-methyllysergic acid butanolamide  4238-82-8   Lysergic Acid Diethylamide/*analogs & derivatives. Minerva Psichiatr 1982;23(1):39
LSD receptor  0   *Receptors, Serotonin Lysergic Acid Diethylamide. Ann NY Acad Sci 1981;367:434
lysergamide  478-94-4   Lysergic Acid Diethylamide/*analogs & derivatives. Act Nerv Super (Praha) 20(1):82;1978

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