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Methadone

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Definition: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)  for methadone maintenance treatment, coordinate with OPIATE SUBSTITUTION TREATMENT   
Pharmacological Action Analgesics, Opioid; Antitussive Agents; Narcotics
See Also Opiate Substitution Treatment
Examples Methadyl Acetate 		Other names addiCare Brand of Methadone Hydrochloride; Yamanouchi Brand of Methadone Hydrochloride; Hydrochloride, Methadone; Symoron; Roxane Brand of Methadone Hydrochloride; Rosemont Brand of Methadone Hydrochloride; Pinewood Brand of Methadone Hydrochloride; Pinadone; Physeptone; Phymet; Phenadone; Pharmascience Brand of Methadone Hydrochloride; Methex; Methadose; Methadone Hydrochloride; Methaddict; Metasedin; Metadol; Martindale Brand of Methadone Hydrochloride; Mallinckrodt Brand of Methadone HydrochlorideDrugs* : WESTADONE; METHADONE HYDROCHLORIDE INTENSOL; METHADOSE; DOLOPHINE HYDROCHLORIDE; METHADONE HYDROCHLORIDE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-dimethylamino-4-(4-hydroxyphenyl)-4-phenylheptan-3-one  41238-35-1   Methadone/*analogs & derivatives. Drug Metab Dispos 1986;14(4):477
2-formamido-4,4-diphenyl-5-heptanone  96740-78-2   Methadone/*analogs & derivatives. Xenobiotica 1985;1592):129
5-methylmethadone  51673-47-3   Methadone/*analogs & derivatives. J Med Chem 1982;25(6):684
isomethadone  466-40-0 6-(dimethylamino)-5-methyl-4,4-diphenyl-3-hexanone  *Methadone.
dipipanone  467-83-4   Methadone/*analogs & derivatives. Br Med J 2(6049):1448;1976; Lancet 2(8087):480;1978
diconal  76391-75-8 3-Hexanone, 4,4-diphenyl-6-(1-piperidinyl)-, hydrochloride, mixt. with 1-(diphenylmethyl)-4-methylpiperazine monohydrochloride  *Cyclizine Drug Combinations Methadone/*analogs & derivatives. Brit Med J 1(6121):1214;1978; Brit Med Soc 2(609):1000;1977; J Ir Med Assoc 66(23):675;1973
normethadone  467-85-6   Methadone/*analogs & derivatives.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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