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Methotrimeprazine

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Definition: A phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)     
Pharmacological Action Analgesics, Non-Narcotic; Antipsychotic Agents; Dopamine Antagonists
Other names Levomepromazine; Levomeprazin; Tizertsin; Tizercine; Tisercin; LevopromazineDrugs* : LEVOPROME
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-desmethyllevomepromazine  37819-98-0   Methotrimeprazine/*analogs & derivatives. Hum Toxicol 1984;3(6):497
methotrimeprazine sulfoxide  7052-08-6   Methotrimeprazine/*analogs & derivatives. Mol Pharmacol 1982;21(2):409
levomepromazine maleate  7104-38-3   Methotrimeprazine/*analogs & derivatives. Acta Pharm Hung 48(4):151;1978
Immobilon  39456-60-5 4,5-epoxy-3-hydroxy-6-methoxy-alpha,17-dimethyl- alpha-propyl-6,14-ethenomorphinan-7-methanol mixt.with (-)-2-methoxy-N,N,beta-trimethyl-10H-pheno thiazine-10-propanamine  *Etorphine *Methotrimeprazine Drug Combinations. Lancet 2(8030):178;1977; Lancet 2(820):95;1973; Vet Rec 100(15):326;1977; Vet Rec 101(11):215;1977; Vet Rec 103(15):334;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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