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Methyl Methanesulfonate

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Definition: An alkylating agent in cancer therapy that may also act as a mutagen by interfering with and causing damage to DNA.     
Pharmacological Action Antineoplastic Agents, Alkylating; Mutagens 		Other names Methylmethane Sulfonate; Methyl Mesilate; Methanesulfonate, Methyl; Mesylate, Methyl; Methylmesilate; Methyl Methylenesulfonate; Methyl Mesylate; Mesilate, Methyl; Dimethylsulfonate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
methyl methanethiosulfonate  2949-92-0   Methyl Methanesulfonate/*analogs & derivatives. Biochem J 161(3):643;1977; Biochem J 177(3):769;1979; Biochemistry 17(25):5382;1978; Biochim Biophys Acta 525(1):61;1978
methylene dimethanesulfonate  156-72-9   Methyl Methanesulfonate/*analogs & derivatives Spermatogenesis/drug effects. Br Med Bull 26(1):83;1970; Chem Biol Interact 11(3):163;1975; Chem Biol Interact 14(1-2):93;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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