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Methylhistamines

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Definition: Histamine substituted in any position with one or more methyl groups. Many of these are agonists for the H1, H2, or both histamine receptors.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dimethylhistaprodifen  0   *Methylhistamines.
methylhistaprodifen  0   *Methylhistamines.
alpha,beta-dimethylhistamine  127607-85-6   *Methylhistamines. Agents Actions Suppl 1991;33:277
alpha-methylhistamine  6986-90-9   *Methylhistamines.
Pharma Action Histamine Agonists 		Agents Actions Suppl 1991;33:69
N-methylhistamine  673-50-7   *Methylhistamines. Anal Biochem 1986;152(1):127
2-amino-5-methylhistamine  89026-20-0   *Methylhistamines. Boll Soc Ital Biol Sper 1984;60(4):789
N,N-dimethylhistamine  673-46-1   *Methylhistamines. J Ethnopharmacol 1982;5(3):359
3-methylhistamine  644-42-8   *Methylhistamines. Neuropharmacology 1981;20(7):711
alpha,N(alpha)-dimethylhistamine  76721-87-4 alpha,N(alpha)-Dimethylhistamine  *Methylhistamines. Arch Pharm (Weinheim) 1980;313(9):780
2-methylhistamine  34392-54-6 1H-Imidazole-4-ethanamine, 2-methyl  *Methylhistamines. Br J Clin Pharmacol 1980;9(5):461
4-methylhistamine  36507-31-0 1H-imidazole-4-ethanamine, 5-methyl  *Methylhistamines Receptors, Histamine H2. Agents Actions 1980;10(1-2):167
5,N'-dimethylhistamine  53966-46-4 N,5-dimethyl-1H-imidazole-4-ethanamine  *Methylhistamines. Eur J Pharmacol 1980;61(4):355
tele-methylhistamine  501-75-7 1-methyl-1H-imidazole-4-ethanamine  *Methylhistamines.
Pharma Action Enzyme Inhibitors 		J Neurochem 32(6):1865;1979
casimiroedine  5853-02-1 4-(2-(N-methyl-N-trans-cinnamoylamino)ethyl)-1- beta-D-glucopyranosylimidazole  *Methylhistamines *Nucleosides. J Am Chem Soc 95(26):8737;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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