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Muscarine

More information in Books or onNLM PubMed
Definition: A toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. It is the first parasympathomimetic substance ever studied and causes profound parasympathetic activation that may end in convulsions and death. The specific antidote is atropine.  /biosyn if permitted by plant; do not confuse with the dye muscarine   
Pharmacological Action Muscarinic Agonists; Parasympathomimetics
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
epimuscarine  0   Muscarine/*analogs & derivatives. J Am Chem Soc 2002 Apr 10;124(14):3608-13
allomuscarine  0   Muscarine/*analogs & derivatives. J Am Chem Soc 2002 Apr 10;124(14):3608-13
4-deoxy-4-fluoromuscarine  132113-37-2   Muscarine/*analogs & derivatives. J Med Chem 1992 Aug 21;35(17):3102-10
5-methylfurtrethonium  14172-53-3   Muscarine/*analogs & derivatives.
Pharma Action Parasympathomimetics 		Acta Biol Med Ger 37(2):347;1978; Acta Biol Med Germ 35(5):657;1976; Comp Gen Pharmacol 2(5):106;1971; Pharmacol Res Commun 9(8):719;1977
desethermuscarone  71788-07-3 ((3-methyl-4-oxocyclopentyl)methyl)trimethylammonium iodide  Muscarine/*analogs & derivatives. Farmaco 30(4):287;1974; J Med Chem 17(4):457;1974
desethermuscarine  99665-31-3 Cyclopentanemethanaminium, 3-hydroxy-N,N,N-4-tetramethyl  Muscarine/*analogs & derivatives. Farmaco 30(4):287-300;1975; J Med Chem 17(4):457;1974
muscarone  13552-60-8   Muscarine/*analogs & derivatives. Br J Pharmacol 52(3):469P;1974; Nature 236(65):112;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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