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Neural Tube Defects

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Definition: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)  do not confuse entry term SPINAL CORD MYELODYSPLASIA with MYELODYSPLASTIC SYNDROMES, a defect of bone marrow formation   
Examples Anencephaly; Arnold-Chiari Malformation; Encephalocele; Meningocele; Meningomyelocele; Pentalogy of Cantrell; Spinal Dysraphism 		Other names Tethered Cord Syndrome; Spinal Cord Myelodysplasia; Neurenteric Cyst; Diastematomyelia; Developmental Defects, Neural Tube; Exencephaly; Craniorachischisis; Diastematomyelias; Defects, Neural Tube; Defect, Neural Tube; Cysts, Neuroenteric; Cysts, Neurenteric; Cyst, Neuroenteric; Cyst, Neurenteric; Craniorachischises; Acranias; Tethered Spinal Cord Syndrome; Occult Spinal Dysraphism Sequence; Occult Spinal Dysraphism; Neuroenteric Cyst
 
SubstanceCAS Registry & nameCategoriesSource
Neural tube defects X-linked  0   *Neural Tube Defects *Genetic Diseases, X-Linked.
Acalvaria  0   *Neural Tube Defects. Am J Med Genet 1993;46:694

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