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Nitracrine

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Definition: Acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis.     
Pharmacological Action Antineoplastic Agents; Nucleic Acid Synthesis Inhibitors 		Other names C283; C 283; Ledakrin; C-283
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine  0   Nitracrine/*analogs & derivatives. Life Sci 2006 Aug 29;79(14):1334-42
4-methoxynitracrine  25799-70-6   Nitracrine/*analogs & derivatives. Xenobiotica 1996 May;26(5):559-69
C 137  13365-37-2 1,3-propanediamine, N'-9-acridinyl-N,N-dimethyl-,  Nitracrine/*analogs & derivatives. Mutat Res 1980 78(1):7
C 264  6237-22-5 N,N-dimethyl-N'-(2-nitro-9-acridinyl)-1,3-propanediamine  Nitracrine/*analogs & derivatives. Ann Med Sect Pol Acad Sci 21(1-2):67;1976
C 684  20063-73-4 1,3-propanediamine, N,N-dimethyl-N'-(1-nitro-9-acridinyl)-, N-oxide  Nitracrine/*analogs & derivatives. Arch Immunol Ther Exp (Warsz) 1979;27(6):749; Arch Immunol Ther Exp 20(3):399;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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