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Pactamycin
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Definition
: Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
Pharmacological Action
Antibiotics, Antineoplastic
;
Protein Synthesis Inhibitors
Substance
CAS Registry & name
Categories
Source
Drugs
*
5''-
fluoropactamycin
0
Pactamycin/*analogs & derivatives.
J Antibiot (Tokyo) 1994 Dec;47(12):1456-65
8''-
hydroxypactamycin
104820-97-5 Benzoic acid, 2-
hydroxy-
6-
methyl-
, (4-
amino-
3-
(((dimethylamino)carbonyl)amino)-
1,2-
dihydroxy-
5-
((3-
(hydroxyacetyl)phenyl)amino)-
3-
(1-
hydroxyethyl)-
2-
methylcyclopentyl)methyl ester, (1S-
(1alpha,2beta,3alpha,3(R*),4alpha,5beta))
Pactamycin/*analogs & derivatives.
J Antibiot (Tokyo) 1986;39(8):1086
cranomycin
11005-94-0
Pactamycin/*analogs & derivatives.
J Antibiot (Tokyo) 1986;39(8):1086