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Pentachlorophenol

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Definition: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.     
Pharmacological Action Environmental Pollutants; Enzyme Inhibitors; Herbicides; Insecticides; Pesticides; Poisons; Uncoupling Agents 		Other names Pentachlorophenate, Sodium; Sodium Pentachlorophenate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pentachlorophenyl palmitate  97457-27-7   *Palmitates Pentachlorophenol/*analogs & derivatives. Bull Environ Contam Toxicol 1985;34(5):661
pentachlorophenol glucuronide  25631-33-8   Pentachlorophenol/*analogs & derivatives. Biochem Pharmacol 1985;34(6):893
2-bromo-3,4,5,6-tetrachlorophenol  94720-18-0   Pentachlorophenol/*analogs & derivatives. J Chromatogr 1984;314:476
methylsulfonylpentachlorobenzene  67646-65-5   *Sulfones Pentachlorophenol/*analogs & derivatives. Dev Toxicol Environ Sci 1980;8:533
Hycolin  11021-24-2 Hycolin  *Cresols *Pentachlorophenol Drug Combinations. Vet Rec 102(13):286;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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