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Peptide Chain Initiation, Translational

More information in Books or onNLM PubMed
Definition: A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.  coordinate with specific peptide; for protein biosynthesis on the ribosome only; for non-ribosomal biosynthesis use PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT   
See Also Codon, Initiator; Peptide Initiation Factors; Protein Synthesis Inhibitors
Other names Protein Translational Initiation; Initiation, Protein Translational; Initiation, Protein Translation; Initiation, Protein Biosynthesis; Initiation, Genetic Translation; Genetic Translation Initiation; Biosynthesis Initiation, Protein; Translational Peptide Chain Initiation; Translational Initiation, Protein; Translation Initiation, Protein; Translation Initiation, Genetic; Protein Chain Initiation, Translational; Protein Biosynthesis Initiation; Chain Initiation, Peptide, Translational; Protein Translation Initiation
 
SubstanceCAS Registry & nameCategoriesSource
polyproanthocyanidin  0   *Phenols Peptide Chain Initiation, Translational/drug effects. FEBS Lett 1990;275(1-2):99

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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