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Phosphoenolpyruvate Carboxylase

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Definition: An enzyme with high affinity for carbon dioxide. It catalyzes irreversibly the formation of oxaloacetate from phosphoenolpyruvate and carbon dioxide. This fixation of carbon dioxide in several bacteria and some plants is the first step in the biosynthesis of glucose. EC 4.1.1.31.  do not confuse with PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP) or PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP)    Other names Carboxylase, Phosphoenolpyruvate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3,3-dichloro-2-dihydroxyphosphinoylmethyl-2-propenoate  0   *Acrylates *Phosphinic Acids Phosphoenolpyruvate Carboxylase/antagonists & inhibitors. Plant Cell Physiol 2000 Jan;41(1):10-5
phosphoenol-3-bromopyruvate  44976-95-6 2-Propenoic acid, 3-bromo-2-(phosphonooxy)  Phosphoenolpyruvate/*analogs & derivatives Phosphoenolpyruvate Carboxylase/antagonists & inhibitors. J Biol Chem 1982;257(24):14603

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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