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Pindolol
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Definition
: A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
Pharmacological Action
Adrenergic beta-Antagonists
;
Antihypertensive Agents
;
Serotonin Antagonists
;
Vasodilator Agents
Examples
Iodocyanopindolol
Other names
Prindolol; LB46; LB 46; Visken; LB-
46
Drugs
*
:
VISKEN
;
PINDOLOL
Substance
CAS Registry & name
Categories
Source
Drugs
*
USVC 6524
4051-88-1
Pindolol/*analogs & derivatives.
pindobind
106469-52-7
Pindolol/*analogs & derivatives.
Pharmacol Biochem Behav 1993 Sep;46(1):67-72
cyanopindolol azide-
2
0
*Azides
Pindolol/*analogs & derivatives.
Biochem Biophys Res Commun 1989;165(1):264
4-
(3-
tert-
butylamino-
2-
hydroxypropoxy)-
2-
carboxyindole
27748-04-5
Pindolol/*analogs & derivatives.
Nippon Yakurigaku Zasshi 1989;94(1):27
N(8)-
bromoacetyl-
N(1)-
3'-
(4-
indolyloxy)-
2'-
hydroxypropyl-
1,8-
diamino-
4-
menthane
106469-51-6
Pindolol/*analogs & derivatives.
Biochem Pharmacol 1988;37(19):3601
pindolol-
NBD
115910-09-3
4-Chloro-7-nitrobenzofurazan/*analogs & derivatives
Pindolol/*analogs & derivatives.
Res Commun Chem Pathol Pharmacol 1988;60(2):147
cyanopindolol
81608-27-7
Pindolol/*analogs & derivatives.
Pharma Action
Adrenergic beta-Antagonists
;
Serotonin Antagonists
Naunyn Schmiedebergs Arch Pharmacol 1985;331(4):398
Br-
AAM-
pindolol
95778-69-1
Pindolol/*analogs & derivatives.
Naunyn Schmiedebergs Arch Pharmacol 1985;328(3):279
N-
(bromoacetylamino)cyanopindolol
95034-01-8 Acetamide, 2-
bromo-
N-
(2-
((3-
((2-
cyano-
1H-
indol-
4-
yl)oxy)-
2-
hydroxypropyl)amino)-
2-
methylpropyl)-
, (2S-
(2alpha,5alpha,6beta))
Pindolol/*analogs & derivatives
Radioisotopes.
Eur J Biochem 1985;146(1):9
hydrochlorothiazide, pindolol drug combination
0
*Hydrochlorothiazide
*Pindolol
Drug Combinations.
Clin Ther 1984;6(4):524
VISKAZIDE
Tenesor
97633-36-8 2H-
1,2,4-
Benzothiadiazine-
7-
sulfonamide, 6-
chloro-
3,4-
dihydro-
, 1,1-
dioxide. mixt. with 1-
((1-
methylethyl)amino)-
3-
((2-
methyl-
1H-
indol-
4-
yl)oxy)-
2-
propanol sulfate (2:1)
*Hydrochlorothiazide
Drug Combinations
Pindolol/*analogs & derivatives.
Biopharm Drug Dispos 1983;4(4):339
nitrisken retard
66848-46-2
*Isosorbide Dinitrate
*Pindolol
Drug Combinations
Delayed-Action Preparations.
Med Welt 1983;34(33-34):906
4-
(2-
hydroxy-
3-
tert-
butylaminopropoxy)-
2-
methylindole
23869-98-9
Pindolol/*analogs & derivatives.
J Chromatogr 1983;273(2):469
bopindolol
69010-88-4 2-
Propanol, 1-
((1,1-
dimethylethyl)amino)-
3-
((2-
methyl-
1H-
indol-
4-
yl)oxy)-
, benzoate (ester), (+-
)
Pindolol/*analogs & derivatives.
Pharma Action
Adrenergic beta-Antagonists
Eur J Clin Pharmacol 1982;22(6):491
clopamide, pindolol drug combination
0
*Clopamide
*Pindolol
Drug Combinations.
Pharma Action
Antihypertensive Agents
Praxis 1982;71(22):949
1-
(indol-
4-
yloxy)-
3-
(1-
(4-
azido-
3-
iodophenyl)-
2-
isobutylamine)-
2-
propanol
77890-09-6 2-
Propanol, 1-
((2-
(4-
azido-
3-
iodophenyl)-
1,1-
dimethylethyl)amino)-
3-
(1H-
indol-
4-
yloxy)-
, (+-
)
*Azides
Pindolol/*analogs & derivatives.
Proc Natl Acad Sci USA 1981;78(3):1609
3-
iodopindolol
76875-01-9 2-
Propanol, 1-
((3-
(iodo-
125I)-
1H-
indol-
4-
yl)oxy)-
3-
((1-
methylethyl)amino)-
, (-
)
Pindolol/*analogs & derivatives.
Pharma Action
Adrenergic beta-Antagonists
J Cyclic Nucleotide Res 1980;6(4):297
mepindolol
23694-81-7
Pindolol/*analogs & derivatives.
Pharma Action
Adrenergic beta-Antagonists
Arzneim Forsch 25(7):1067;1975; Br J Pharmacol 47(3):621P;1973; Eur J Clin Pharmacol 15(1):1;1979; Int J Clin Pharmacol Biopharm 15(7):325;1977; Int J Clin Pharmacol Biopharm 15(8):381;1977; Int J Clin Pharmacol Biopharm 16(6):249;1978; Int J Clin Pharmacol Biopharm 16(7):313;1978; J Chromatogr 1980;181(1):67; Wien Med Wochenschr 1978:129(19):541; Z Kardiol 67:46;1978; Z Kardiol 67:51;1978
hydroxybenzylpindolol
69925-27-5
Pindolol/*analogs & derivatives.
Arch Internat Physiol Biochim 86(2):453;1978; Helv Chim Acta 60(4):1398;1977; J Cyclic Nucleotide Res 5(2):99;1979; Jpn J Clin Med 34(3):534;1976; Life Sci 19(2):243;1976; Life Sci 21(3):403;1977; Rec Prog Hormone Res 32:567-639;1976
iodohydroxybenzylpindolol
58946-16-0 4-
(2-
((2-
hydroxy-
3-
(1H-
indol-
4-
yloxy)propyl)amino)-
2-
methylpropyl)iodophenol
Pindolol/*analogs & derivatives.
Adv Cyclic Nucleotide Res 9:411;1978; Adv Cyclic Nucleotide Res 9:465;1978; Endocrinology 100(6):1703;1977; Endocrinology 101(6):1839;1977; FEBS Lett 76(2):302;1977; J Biol Chem 251(23):7572;1976; J Biol Chem 251(5):1221-39;1976; J Biol Chem 252(16):5761;1977; J Biol Chem 252(4):1293;1977; J Biol Chem 253(15):5418;1978; J Clin Invest 1980;65(5):1111; J Clin Invest 1980;65(5):949; J Cyclic Nucleotide Res 2(3):149;1976; J Histochem Cytochem 1979;27(10):1308; J Pharmacol Exp Ther 1979;211(3):502; J Pharmacol Exp Ther 1980;212(3):503; Mol Biol Pharmacol Cyclic Nucleotides W3 SY1056 v.1:13;1978