encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 
ψ 

Polymyxins

More information in Books or onNLM PubMed
Definition: Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.     
Pharmacological Action Anti-Bacterial Agents
Examples Colistin; Polymyxin B 		Other names Polymyxin; Polymyxin M
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
polymyxin B2  0   *Polymyxins. Nature. 1964 Oct 10;204:185.
polymyxin B6, Paenibacillus polymyxa  0   *Polymyxins. Peptides. 2011 Sep;32(9):1917-23.
polymyxin B3, dansyllysyl(1)  0   *Polymyxins Fluorescent Dyes. Anal Biochem 2011 Feb 15;409(2):273-83
NAB 739 peptide  0   *Polymyxins. J Antimicrob Chemother 2009 Nov;64(5):1067-70
NAB 7061 peptide  0   *Polymyxins. J Antimicrob Chemother 2009 Nov;64(5):1067-70
paenimyxin  0   *Polymyxins. Pest Manag Sci 2007 Mar;63(3):269-75
polymyxin B(1)  4135-11-9   Polymyxins/*analogs & derivatives. J Pept Res 1999 May;53(5):501-6
deacylpolymyxin B  76014-40-9 Polymyxin B1, 1-(L-2,4-diaminobutanoic acid)  *Polymyxins. J Antibiot (Tokyo) 1991;44(5):517
pelargonoyl cyclic decapeptide polymyxin M(1)  77554-83-7 Cyclic(L-alpha,gamma-diaminobutyryl-Ngamma-(1-oxononyl)-L-alpha,gamma-diaminobutyryl-L-alpha,gamma-diaminobutyryl-D-leucyl-L-threonyl-L-alpha,gamma-diaminobutyryl-L-alpha,gamma-diaminobutyryl-L-threonyl-L-alpha,gamma-diaminobutyryl-L-threonyl), pentahydr  *Polymyxins. Pharmazie 1980;35(12):761
Terracortril Gel Sterajet  79028-54-9   *Hydrocortisone *Oxytetracycline *Polymyxins Drug Combinations Administration, Intravaginal. Fortschr Med 96(1):35;1978
polymyxin T(1)  63700-39-0 Polymyxin B1, 10-L-leucine  *Polymyxins. J Antibiot (Tokyo) 30(5):427;1977
polymyxin S(1)  63700-38-9 Polymyxin D1, 6-D-phenylalanine  *Polymyxins. J Antibiot (Tokyo) 30(5):427;1977
polypeptin  1404-32-6   *Polymyxins. J Med Chem 19(10):1228;1976
polymagma  78393-44-9 D-Streptamine, O-2-deoxy-2--(methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt), mixt. with polymyxin B sulfate  *Dihydrostreptomycin Sulfate *Pectins *Polymyxins Drug Combinations. Blood 45(2):213;1975
lubasporin  0   *Benzalkonium Compounds *Polymyxins Drug Combinations. Int J Nurs Stud 12(1):33;1975
UCB 630  78891-94-8 Neomycin, sulfate (salt), mixt. with (3-(acetylamino)-4-hydroxyphenyl)arsonic acid, nystatin and polymyxin B sulfate  *Arsenicals *Neomycin *Nystatin *Polymyxins Drug Combinations. Brux Med 54(8):447;1974

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy