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Pregnanediol

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Definition: An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
hoodigogenin A  0   Pregnanediol/*analogs & derivatives. Planta Med. 2010 Jan;76(1):62-9
20-N-methylpiperidin-2-yl-5-pregnan-3,20-diol  0   Pregnanediol/*analogs & derivatives. Acta Crystallogr B 2001 Oct;57(Pt 5):714-21
20-piperidin-2-yl-5-pregnan-3,20-diol  0   Pregnanediol/*analogs & derivatives. Acta Crystallogr B 2001 Oct;57(Pt 5):714-21
pregnanediol-3 delta-glucuronide  0   Pregnanediol/*analogs & derivatives. J Wildl Dis 1992 Oct;28(4):590-7
11-keto-pregnanediol  6815-48-1 Pregnan-11-one, 3,20-dihydroxy-, (3alpha,5beta,20S)  Pregnanediol/*analogs & derivatives. Acta Biochim Biophys Acad Sci Hung 1982;16(3-4):179
pregnane-3,20-diol 3,20-disulfate  27935-53-1   Pregnanediol/*analogs & derivatives. J Steroid Biochem 1980;13(12):1473
pregnane-3,20-diol 3-sulfate  65423-37-2 Pregnane-3,20-diol, 3-(hydrogen sulfate), (3beta,5alpha,20S)  Pregnanediol/*analogs & derivatives. J Steroid Biochem 1980;13(12):1473
pregnanediol-3 alpha-glucuronide  1852-49-9 (3 alpha,5 beta,20S)-20-hydroxypregnan-3-yl beta-D-glucopyranosiduronic acid  Pregnanediol/*analogs & derivatives. J Steroid Biochem 11(2):1165;1979
allopregnane-3,20-diol  4479-11-2 (3 alpha,5 alpha,20S)-pregnane-3,20-diol  *Pregnanediol Stereoisomerism. Biochem Biophys Res Commun 84(4):1003;1978; Endocrinology 103(4):1039;1978; Proc Soc Exp Biol Med 161(1):66;1979
17-deoxycortolonic acid  60918-94-7 Pregnan-21-oic acid, 3,20-dihydroxy-11-oxo-, (3alpha,5beta,20S)  Pregnanediol/*analogs & derivatives. J Clin Endocrinol Metab 43:696;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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