encyclopedia of medical concepts
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Probucol
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Definition
: A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Pharmacological Action
Anticholesteremic Agents
;
Antioxidants
Other names
DH581; DH 581; Superlipid; Panavir; Lurselle; Lorelco; Hoechst Brand of Probucol; DH-
581; Biphenabid; Aventis Brand of Probucol; Almirall Brand of Probucol
Drugs
*
:
LORELCO
Substance
CAS Registry & name
Categories
Source
Drugs
*
camobucol
216167-92-9
Probucol/*analogs & derivatives.
J Med Chem 2004 Dec 2;47(25):6420-32
succinobucol
216167-82-7
Probucol/*analogs & derivatives.
Circulation 2003 Feb 4;107(4):552-8
bis-
(3-
(3',5'-
di-
tert-
butyl-
4'-
hydroxyphenyl)propyl)sulfide
0
Probucol/*analogs & derivatives.
Vopr Med Khim 2001 Sep-Oct;47(5):517-25
CGP 2881
0
Probucol/*analogs & derivatives.
Atherosclerosis 1999 Jun;144(2):343-55
fenbutol
0
Probucol/*analogs & derivatives.
Kardiologiia 1993;33(7):7-10
S 12340
144754-35-8 1-
Oxa-
3,8-
diazaspiro(4.5)decan-
2-
one, 8-
(3-
((3,5-
bis(1,1-
dimethylethyl)-
4-
hydroxyphenyl)thio)propyl)
*Spiro Compounds
Probucol/*analogs & derivatives.
Eur J Pharmacol 1993 Oct 1;248(3):263-72
MDL 27968
27428-13-3
Probucol/*analogs & derivatives.
Lipids 1992 Jul;27(7):543-50
MDL 29311
129895-82-5
Probucol/*analogs & derivatives.
Arterioscler Thromb 1991;11(5):1266