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Proline Oxidase

More information in Books or onNLM PubMed
Definition: The first enzyme of the proline degradative pathway. It catalyzes the oxidation of proline to pyrroline-5-carboxylic acid in the presence of oxygen and water. The action is not reversible. The specific activity of proline oxidase increases with age. EC 1.5.3.-.      Other names Proline Dehydrogenase; Oxidase, Proline; Dehydrogenase, Proline
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Hyperprolinemia  0   *Amino Acid Metabolism, Inborn Errors Proline Oxidase/deficiency.
proline dehydrogenase (oxidase) 2  EC 1.5.3.-   *Proline Oxidase. Proc Natl Acad Sci U S A 2002 Mar 19;99(6):3717-22
4-methyleneproline  20309-87-9   Proline/*analogs & derivatives Proline Oxidase/antagonists & inhibitors. Biochim Biophys Acta 1993 Sep 3;1202(1):77-81
PutA protein, Bacteria  0   *Bacterial Proteins *Membrane Proteins Oxidoreductases Acting on CH-NH Group Donors Proline Oxidase Repressor Proteins Escherichia coli Proteins. J Biol Chem 1993 April 25;268(12):8972-79

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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