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Ribonuclease, Pancreatic

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Definition: An enzyme that catalyzes the endonucleolytic cleavage of pancreatic ribonucleic acids to 3'-phosphomono- and oligonucleotides ending in cytidylic or uridylic acids with 2',3'-cyclic phosphate intermediates. EC 3.1.27.5.      Other names Ribonuclease A; RNase A; RNase, Pancreatic; Pancreatic Ribonuclease; Ribonuclease I; Ribonuclease (Pancreatic); RNase I; Pancreatic RNase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Ang4 protein, mouse  EC 3.1.27.5   *Ribonuclease, Pancreatic. Biochemistry 2007 Mar 6;46(9):2431-43
pancreatic ribonuclease B, bovine  EC 3.1.27.5   *Ribonuclease, Pancreatic. Biochemistry 2005 Jul 19;44(28):9817-23
pancreatic RNase 2, human  EC 3.1.27.5   *Ribonuclease, Pancreatic. J Clin Endocrinol Metab 2003 Jun;88(6):2900-7
recombinant fusion protein RNase1-IL-2  0   *Interleukin-2 *Ribonuclease, Pancreatic Recombinant Fusion Proteins Immunotoxins. Cytokine 2000 Jun;12(6):786-90
Ang2 protein, mouse  EC 3.1.27.5   *Ribonuclease, Pancreatic. Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4331-5
RNase A (1-123)-3-(2-naphthyl)alanine amide  0   *Peptide Fragments *Ribonuclease, Pancreatic Alanine/*analogs & derivatives. Anal Biochem 1993 Feb 15;209(1):20-31
ribonuclease A (21-124)  EC 3.1.27.-   *Peptide Fragments *Ribonuclease, Pancreatic. Biotechnology 1992 Jan;10(1):86-91
ribonuclease A S-peptide  0   *Peptide Fragments *Ribonuclease, Pancreatic. Biochemistry 1989;28(12):5256
angiogenin, methionyl-(-1)  120298-94-4   *Ribonuclease, Pancreatic. Anal Biochem 1988;175(2):450
ribonuclease A (19-26)  0   *Peptide Fragments *Ribonuclease, Pancreatic. Biochem Biophys Res Commun 1987;143(1):248
adenosine 3'-phosphate 5'-diphosphate  13400-10-7   Adenosine Diphosphate/*analogs & derivatives Ribonuclease, Pancreatic/antagonists & inhibitors. J Biol Chem 1986;261(17):7603
angiogenin  EC 3.1.27.-   *Ribonuclease, Pancreatic.
Pharma Action Angiogenesis Inducing Agents
Science 1985;230(4722):161
ribonuclease A, C-peptide  0   *Peptide Fragments *Ribonuclease, Pancreatic. J Mol Biol 1982;162(1):187
2'P-ADP  4457-01-6 adenosine 5'-(trihydrogen diphorphate), 2'-(dihydrogen phosphate)  Adenosine Diphosphate/*analogs & derivatives Ribonuclease, Pancreatic/antagonists & inhibitors. Methods Enzymol 1980;66:112

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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