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Ribose-Phosphate Pyrophosphokinase

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Definition: An enzyme that catalyzes the formation of phosphoribosyl pyrophosphate from ATP and ribose-5-phosphate. EC 2.7.6.1.  DF: note short X ref    Other names Phosphoribosyl Pyrophosphate Synthetase; PRPP Synthetase; Synthetase, Phosphoribosyl Pyrophosphate; Synthetase, PRPP; Synthetase, 5-Phospho-alpha-D-Ribose 1-Diphosphate; Ribose Phosphate Pyrophosphokinase; Pyrophosphokinase, Ribosephosphate; Pyrophosphokinase, Ribose-Phosphate; Pyrophosphate Synthetase, Phosphoribosyl; 5 Phospho alpha D Ribose 1 Diphosphate Synthetase; 1-Diphosphate Synthetase, 5-Phospho-alpha-D-Ribose; Ribosephosphate Pyrophosphokinase; PRibPP Synthetase; 5-Phospho-alpha-D-Ribose 1-Diphosphate Synthetase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Phosphoribosylpyrophosphate synthetase deficiency  0   *Purine-Pyrimidine Metabolism, Inborn Errors Ribose-Phosphate Pyrophosphokinase/deficiency.
PRPS1 protein, human  EC 2.7.6.1   *Ribose-Phosphate Pyrophosphokinase. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 May 1;62(Pt 5):432-4
NSC 283867  0   *Pyrimidine Nucleosides Ribose-Phosphate Pyrophosphokinase/antagonists & inhibitors. Carbohydrate Res 44(2):169;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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