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RNA, Messenger

More information in Books or onNLM PubMed
Definition: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.  IM; /drug eff /ultrastruct permitted; DF: note short X ref   
Examples Codon; Riboswitch; RNA Caps; RNA, Messenger, Stored; RNA Splice Sites; Untranslated Regions
Other names mRNA, Polyadenylated; mRNA, Non-Polyadenylated; mRNA; RNA, Polyadenylated; RNA, Messenger, Polyadenylated; Poly(A)+ mRNA; Poly(A)+ RNA; Poly(A) Tail; Messenger RNA, Polyadenylated; Messenger RNA; mRNA, Non Polyadenylated; RNA, Polyadenylated Messenger; Polyadenylated RNA; Polyadenylated Messenger RNA; Non Polyadenylated mRNA; Polyadenylated mRNA; Poly(A) RNA; Non-Polyadenylated mRNA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
HYMAI, RNA  0   *RNA, Messenger. Cytogenet Genome Res. 2006;113(1-4):247-52
FASAS gene product, human  0   *RNA, Messenger. Hum Mol Genet 2005 Jun 1;14(11):1465-74
PAPPAS gene product, human  0   *RNA, Messenger. Placenta 2004 Sep-Oct;25(8-9):684-93
DAOAAS gene product, human  0   *RNA, Messenger. Biochem Biophys Res Commun 2004 Jul 9;319(4):1281-6
NCRNA00253 gene product, human  0   *RNA, Messenger. Prostate 2003 Jul 1;56(2):123-30
DISC2 gene product, human  0   *RNA, Messenger. Psychiatr Genet 2001 Jun;11(2):71-8
non-coding transcript abundantly expressed in brain  0   *RNA, Messenger. Neuroscience 2001;108(2):207-15
adapt73  0   *RNA, Messenger. Surgery 1997 May;121(5):581-7
tmRNA  0   *RNA, Bacterial RNA, Messenger RNA, Transfer. Cell 1995 Oct 20;83(2):227-35
oligo(U+)RNA  0   *RNA, Messenger *Uracil Nucleotides. Biochemistry 1981;20(19):5359
mitochondrial messenger RNA  0   *RNA, Messenger Mitochondria. Nature 1981;290(9):465

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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