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Saralasin

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Definition: An octapeptide analog of angiotensin II (bovine) with amino acids 1 and 8 replaced with sarcosine and alanine, respectively. It is a highly specific competitive inhibitor of angiotensin II.     
Pharmacological Action Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents
Other names 1-Sarcosine-8-Alanine Angiotensin II; 1-Sar-8-Ala Angiotensin II; P-113; Sar Arg Val Tyr Val His Pro Ala; Hydrated Saralasin Acetate; Anhydrous Saralasin Acetate; Angiotensin II, 1-Sarcosine-8-Alanine; Angiotensin II, 1-Sar-8-Ala; Acetate, Hydrated Saralasin; 1 Sarcosine 8 Alanine Angiotensin II; angiotensin II, sarcosyl(1)-alanine(8); 1 Sar 8 Ala Angiotensin II; angiotensin II, Sar(1)-Ala(8); Saralasin Acetate, Hydrated; Saralasin Acetate, Anhydrous; Saralasin Acetate; Sar-Arg-Val-Tyr-Val-His-Pro-Ala; P-113 Acetate; 1-Sar-8-Ala-angiotensin II; (Sar1,Val5,Ala8)Angiotensin IIDrugs* : SARENIN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
angiotensin II, 1-Sar-5-Ile-8-Ala  38027-95-1   Saralasin/*analogs & derivatives. Endocrinology 1980;107(6):1855

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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