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Glycine Hydroxymethyltransferase
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Definition
: A pyridoxal phosphate enzyme that catalyzes the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyzes the reaction of glycine with acetaldehyde to form L-threonine. EC 2.1.2.1.
Other names
Threonine Aldolase; Serine Transhydroxymethylase; Serine Hydroxymethyltransferase; Serine Hydroxymethylase; Serine Aldolase; Transhydroxymethylase, Serine; Hydroxymethyltransferase, Serine; Hydroxymethyltransferase, Glycine; Hydroxymethylase, Serine; Aldolase, Threonine; Aldolase, Allothreonine; Allothreonine Aldolase; Aldolase, Serine
Substance
CAS Registry & name
Categories
Source
Drugs
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Shmt1 protein, mouse
EC 2.1.2.1
*Glycine Hydroxymethyltransferase.
Cancer Res. 2011 Mar 15;71(6):2098-107
SHMT1 protein, human
EC 2.1.2.1
*Glycine Hydroxymethyltransferase.
Gene 1998 Apr 14;210(2):315-24
SHM2 protein, Arabidopsis
EC 2.1.2.1
*Glycine Hydroxymethyltransferase
*Arabidopsis Proteins
Mitochondrial Proteins.
Plant Physiol 2006 Jan;140(1):59-66
SHM1 protein, Arabidopsis
EC 2.1.2.1
*Glycine Hydroxymethyltransferase
*Arabidopsis Proteins
Mitochondrial Proteins.
Plant Physiol 2006 Jan;140(1):59-66
SHMT1 protein, Arabidopsis
EC 2.1.2.1
*Glycine Hydroxymethyltransferase
*Arabidopsis Proteins.
Plant J 2005 Feb;41(3):386-99