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Showdomycin

More information in Books or onNLM PubMed
Definition: 3-beta-D-Ribofuranosylmaleimide. Antineoplastic antibiotic isolated from Streptomyces showdoensis. It is possibly active also as a sulfhydryl reagent.  an antineoplastic antibiotic   
Pharmacological Action Antibiotics, Antineoplastic; Sulfhydryl Reagents
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2'-deoxyshowdomycin  64915-00-0 1H-Pyrrole-2,5-dione, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)  Showdomycin/*analogs & derivatives. J Biomol Struct Dyn 1994 Apr;11(5):1107-31
3-(2,3-(isopropylidenedioxy)-4-(pivaloxymethyl)cyclopentyl)maleimide  144674-69-1   Showdomycin/*analogs & derivatives. Nucleic Acids Symp Ser 1991;25:187-8
3-(3-O-benzyl-1,2-O-isopropylidene-erythrofuranos-4-yl)maleimide  124484-37-3   Showdomycin/*analogs & derivatives. Carbohyr Res 1989;188:19
3-(1,2-O-isopropylidene-threofuranos-4-yl)maleimide  124484-34-0   Showdomycin/*analogs & derivatives. Carbohydr Res 1989;188:19
showdomycin triphosphate  67739-86-0   Showdomycin/*analogs & derivatives. Cancer Lett 4:259;1978
showdomycin diphosphate  79084-77-8 1H-Pyrrole-2,5-dione, 3-(5-O-(hydroxy(phosphonooxy)phosphinyl)-beta-D-ribofuranosyl)  Showdomycin/*analogs & derivatives. Cancer Lett 4:259;1978
showdomycin 5'-phosphate  40853-66-5   Showdomycin/analogs & derivatives Sulfhydryl Reagents. Biochem Biophys Res Commun 49(4):1007;1972; Cancer Lett 4:259;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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