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Supranuclear Palsy, Progressive

More information in Books or onNLM PubMed
Definition: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)      Other names Steele-Richardson-Olszewski Syndrome; Progressive Supranuclear Ophthalmoplegia; Ophthalmoplegia, Progressive Supranuclear; Syndrome, Steele-Richardson-Olszewski; Supranuclear Palsies, Progressive; Supranuclear Ophthalmoplegias, Progressive; Supranuclear Ophthalmoplegia, Progressive; Steele Richardson Olszewski Syndrome; Steele Richardson Olszewski Disease; Progressive Supranuclear Palsy; Progressive Supranuclear Palsies; Progressive Supranuclear Ophthalmoplegias; Ophthalmoplegias, Progressive Supranuclear; Steele-Richardson-Olszewski Disease; Palsy, Progressive Supranuclear
 
SubstanceCAS Registry & nameCategoriesSource
Familial progressive supranuclear palsy  0   *Supranuclear Palsy, Progressive.
Progressive supranuclear palsy atypical  0   *Supranuclear Palsy, Progressive.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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