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Sydnones

More information in Books or onNLM PubMed
Definition: OXADIAZOLES bearing an oxygen at the 5-position. They are mesoionic, with delocalized positive and negative charges.     
Examples Molsidomine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
OF 900  0   *Sydnones. Biull Eksp Biol Med 1997 Jul;124(7):13-5
3-methylsydnone-5-nitrosimine  0   *Sydnones. Arch Pharm (Weinheim) 1995 Jan;328(1):71-5
sydnogluton  153216-47-8 L-Glutamic acid, mixt. with 3-(1-methyl-2-phenylethyl)-N-((phenylamino)carbonyl)sydnone imine  *Glutamates *Sydnones Drug Combinations. Eksp Klin Farmakol 1993 May-Jun;56(3):10-5
pirsidomine  132722-74-8 Sydnone imine, 3-(2,6-dimethyl-1-piperidinyl)-N-(4-methoxybenzoyl)-, cis  *Sydnones. J Cardiovasc Pharmacol 1991 Oct;18(4):522-7
3-(cis-2,6-dimethylpiperidino)sydnonimine  137500-42-6 Sydnone imine, 3-(2,6-dimethyl-1-piperidinyl)-, cis  *Sydnones.
Pharma Action Vasodilator Agents 		J Pharm Exp Ther 1992 Feb;260(2):668-75
OF 743  137012-39-6   *Sydnones. Biol Nauki 1991;7:52-7
3-(2-phenylethyl)-4-methylsydnone  114886-35-0   *Sydnones. Biochemistry 1988;27(13):4805
3-(2-(2,4,6-trimethylphenyl)thioethyl)-4-methylsydnone  53492-67-4   *Sydnones. FEBS Lett 1986;197(1-2):17
3-(2-(4-methylphenyl)thioethyl)-5-sydnone  96991-48-9   *Sydnones. Arzneimittelforsch 1985;35(3):578
sydnophen  22293-47-6 3-(1-methyl-2-phenylethyl)sydnone imine, monohydrochloride  *Sydnones. Farmakol Toksikol 40(1):50;1977; Farmatsiia 25(3):41;1976; Vopr Med Khim 25(4):391;1979
3-tert-butylsydnone  6939-25-9   *Sydnones. J Pharm Sci 65(1):109;1976
sidnocarb  34262-84-5   *Sydnones.
Pharma Action Central Nervous System Stimulants ; Anticonvulsants ; Antidepressive Agents ; Sympathomimetics 		Acta Pharm Hung 47(1):48;1977; Acta Pharm Hung 48 (suppl):23;1978; Biull Eksp Biol Med 88(7):38;1979; Biull Eksp Biol Med 9:303;1977; Cesk Psychiatr 71(2-3):155;1975; Farmakol Toksikol 2:133;1977; Farmakol Toksikol 38(3):263-267;1975; Farmakol Toksikol 39(1):9;1976; Farmakol Toksikol 40(6):691;1977; Farmakol Toksikol 41(1):5;1978; Farmakol Toksikol 41(6):650;1978; Psychiatr Neurol Med Psychol (Leipz) 28(10):609;1976; Schweiz Arch Neurol Neurochir Psychiatr 120(2):323;1977; Vopr Med Khim 25(4):391;1979; Xenobiotica 1979;9(8):511; Zh Nevropatol Psikhiatr 74(4):594;1974
3-benzylsydnone-4-acetamide  14504-15-5   *Sydnones. Gann 65(3):273;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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