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Tenuazonic Acid
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Definition
: 3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.
an antineoplastic antibiotic
Pharmacological Action
Antibiotics, Antineoplastic
;
Antiviral Agents
Other names
Acid, Tenuazonic
Substance
CAS Registry & name
Categories
Source
Drugs
*
3-
acetyl-
5-
iso-
butyltetramic acid
0
Tenuazonic Acid/*analogs & derivatives.
Nat Prod Commun. 2009 Nov;4(11):1473-6
reutericyclin
0 (5R)-
1-
(2-
decenoyl)-
2-
hydroxy-
3-
acetyl-
5-
isobutyl-
delta2-
pyrroline-
4-
one
Tenuazonic Acid/*analogs & derivatives
Lactobacillus.
Appl Environ Microbiol. 2000 Oct;66(10):4325-33; Appl Microbiol Biotechnol. 2004 Apr;64(3):326-32. Epub 2004 Jan 21
3-
acetyl-
5-
isopropyltetramic acid
2113-91-9
Tenuazonic Acid/*analogs & derivatives.
J Chromatogr 1991;566(1):195