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Thioacetazone

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Definition: A thiosemicarbazone that is used in association with other antimycobacterial agents in the initial and continuation phases of antituberculosis regimens. Thiacetazone containing regimens are less effective than the short-course regimen recommended by the International Union Against Tuberculosis and are used in some developing countries to reduce drug costs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p217)     
Pharmacological Action Antitubercular Agents 		Other names Amithiozone; TBI698; TBI 698; TB I698; TB I 698; Thioacetazon; Thiacetazone; TBI-698; TB I-698; Parazone; Conteben; Ambathizon
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
KBF 611  0   Thioacetazone/*analogs & derivatives. Arch Pharm Res. 2009 Oct;32(10):1453-60
SRI 224  0   Thioacetazone/*analogs & derivatives. Antimicrob Agents Chemother 2003 Aug;47(8):2685-7
SRI 286  0   Thioacetazone/*analogs & derivatives. Antimicrob Agents Chemother 2003 Aug;47(8):2685-7
TB 450  62682-46-6   *Isoniazid *Thioacetazone Drug Combinations. Ethiop Med J 1980;18(4):175

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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