encyclopedia of medical concepts
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Thiram

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Definition: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations.     
Pharmacological Action Fungicides, Industrial; Mutagens 		Other names Thiram Novartis Brand; Disulfide, Tetramethylthiuram; Disulfide, TMT; Thiuram D; Thiuram; Tetramethylthiuram Disulfide; TMT Disulfide; Sadoplon 75; Novartis Brand of Thiram; Nobecutan; Bacteriostat; TMTD
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dipentamethylene thiuram monosulfide  0   *Piperidines Thiram/*analogs & derivatives Peptidylprolyl Isomerase/antagonists & inhibitors. Biochem Biophys Res Commun 2009 Jul 3;384(3):394-8
hexathiuram  61512-80-9   *Thiram *Hexachlorobenzene Air Pollutants, Occupational. Gig Sanit 1992 Mar;(3):42-3
nobecutane spray  0   *Acrylic Resins *Thiram Drug Combinations Occlusive Dressings. J Dermatol Surg Oncol 1986;12(4):386
oxafun  37244-87-4   *Carboxin *Thiram. Acta Microbiol Pol 1983;32(2):185
tetramethylthiuram monosulfide  97-74-5   Thiram/*analogs & derivatives. Environ Res 1982;28(1):199
Agronex  8015-42-7   *Lindane *Thiram. Rocz Akad Med Bialymstoku 21:49;1977
fentiuram  8066-27-1   *Lindane *Chlorophenols *Thiram. Veterinariia 12:67;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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