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Thrombasthenia

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Definition: A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).     
See Also Platelet Glycoprotein GPIIb-IIIa Complex
Other names Glanzmann Thrombasthenia; Thrombasthenias; Thrombasthenia, Glanzmann; Platelet Glycoprotein 2b 3a Deficiency; Thrombasthenia of Glanzmann and Naegeli; Platelet Glycoprotein 2b-3a Deficiency; Platelet Fibrinogen Receptor, Deficiency of; Glanzmann Thrombasthenia, Type A; Deficiency of GP 2b 3a Complex
 
SubstanceCAS Registry & nameCategoriesSource
Schlegelberger Grote syndrome  0   *Congenital Abnormalities *Deafness *Thrombasthenia.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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