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Urotensins

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Definition: Teleost hormones. A family of small peptides isolated from urophyses of bony fishes. They have many different physiological effects, including long-lasting hypotensive activity and have been proposed as antihypertensives. There are at least four different compounds: urotensin I, urotensin II, urotensin III, and urotensin IV.  antihypertensives; from urophyses of fish; /biosyn /physiol permitted   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
urotensin II(4-11), Cha(6)  0   *Peptide Fragments *Urotensins. J Med Chem 2006 Nov 30;49(24):7234-8
urotensin II (4-11), Pen(5)-Trp(7)-Orn(8)  0   *Peptide Fragments *Urotensins. Br J Pharmacol 2003 Dec;140(7):1155-8
(Orn8)urotensin-II  0   *Urotensins. Br J Pharmacol 2002 Oct;137(3):311-4
preprourotensin II  0   *Protein Precursors *Urotensins. Biochem Biophys Res Commun 1999 Nov;265(1):123-9
urotensin II  9047-55-6   *Urotensins. Gen Comp Endocrinol 1981;43(4):479
urotensin I  9047-54-5   *Urotensins. Gen Comp Endocrinol 1981;43(4):479

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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