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Vasopressins

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Definition: Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.  general or unspecified; prefer specifics; /secret: consider also INAPPROPRIATE ADH SYNDROME   
Pharmacological Action Antidiuretic Agents; Hemostatics; Vasoconstrictor Agents
See Also Inappropriate ADH Syndrome; Receptors, Vasopressin
Examples Arginine Vasopressin; Lypressin; Ornipressin 		Other names beta-Hypophamine; Antidiuretic Hormones; beta Hypophamine; Vasopressin Monarch Brand; Vasopressin (USP); Vasopressin; Pitressin; Parke-Davis Brand of Vasopressin (USP); Monarch Brand of Vasopressin; American Regent Brand of Vasopressin; American Pharmaceutical Brand of Vasopressin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
vasopressin, Phe(2)-Ile(3)-Hgn(4)-Orn(iPr)(8)  0   *Vasopressins Receptors, Vasopressin/agonists. J Pharmacol Exp Ther 2011 Jun;337(3):786-96
NOX-F37 oligoribonucleotide  0   *Oligoribonucleotides Vasopressins/antagonists & inhibitors. Proc Natl Acad Sci U S A 2006 Mar 28;103(13):5173-8
benzylcarbonyl-4-benzoylphenylalanyl-phenylalanyl-glutaminyl-asparaginyl-arginyl-prolyl-arginyl-3-iodotyrosinamide  0   *Oligopeptides Vasopressins/antagonists & inhibitors. J Med Chem 2005 May 5;48(9):3379-88
iodo-lin-vasopressin  0   *Vasopressins. J Neuroendocrinol 2002 May;14(5):349-53
proAVP hormone  0   *Vasopressins. Neuroendocrinol Lett 2002 Feb;23(1):33-44
AVP protein, human  0   *Neurophysins *Protein Precursors *Vasopressins Diabetes Insipidus. Eur J Endocrinol 2001 Oct;145(4):439-44
F992 peptide  0   *Oligopeptides Vasopressins. Eur J Clin Pharmacol 1999 Jun;55(4):293-8
F-180 vasoconstrictor peptide  0   *Vasopressins. Hepatology 1998 Feb 27(2):351-6
hydroxyphenylacetyl-methyltyrosyl-phenylalanyl-glutaminyl-asparaginyl-arginyl-prolyl-argininamide  0   *Oligopeptides Vasopressins/antagonists & inhibitors. Neuroendocrinology 1995 Aug;62(2):135-46
vasopressin, (beta-mercapto-(beta,beta)-cyclopentamethylenepropionic acid)-Phe(2)-Ile(4)-Ala(9)  0   *Vasopressins Receptors, Vasopressin/antagonists & inhibitors. J Endocrinol 1995 Oct;147(1):59-65
preprovasopressin  0   *Protein Precursors *Vasopressins. Biochimie 1994;76(3-4):315-9
vasopressinase-altered vasopressin  84953-75-3   *Vasopressins Hypertension. Am J Perinatol 1993 Mar;10(2):160-3
vasopressin, des-Gly  0   *Vasopressins. Comp Biochem Physiol (C) 1991;98(2-3):281
vasopressin, beta-mercapto beta,beta-cyclopentamethylenepropionic acid(1)-O-ethyl-Tyr(2)-Val(4)-Cit(8)  92954-83-1   *Vasopressins. Brain Res 1990;527(1):167
oxytocin, beta-mercapto-beta,beta-cyclopentamethylenepropionic acid-Trp(2)-Phe(3)-Ile(4)-Arg(8)  130155-44-1   *Vasopressins. Am J Obstet Gynecol 1990;163(6 Pt 1):1875
SK&F 105494  0   Arginine Vasopressin/*analogs & derivatives Vasopressins/antagonists & inhibitors. J Pharmacol Exp Ther 1988;245(1):211
Glanduphen  80955-19-7   *Oxytocin *Vasopressins Drug Combinations. Arch Exp Veterinarmed 1984;38(2):133
lidocaine, norepinephrine, vasopressin drug combination  0   *Lidocaine *Norepinephrine *Vasopressins. Schweiz Monatsschr Zahnmed 1984;94(4):307
pitressin tannate  0   *Vasopressins. Internat J Clin Pharmacol Biopharm 16(1):10;1978; Neurol Surg (Tokyo) 6(8):795;1978PITRESSIN TANNATE
pressinoic acid  35748-51-7   *Vasopressins. J Am Chem Soc 94:982;1972; Proc Soc Exp Biol Med 143(4):954;1973
pressinamide  27759-18-8   *Vasopressins. J Am Chem Soc 94:982;1972; Proc Soc Exp Biol Med 143(4):954:1973
vasopressin, epsilon-hydroxy-Nle(8)  43210-81-7   *Vasopressins. J Med Chem 17(2):252;1974
vasopressin, homo-Nle(8)  43157-38-6   *Vasopressins Blood Pressure/drug effects Diuresis/drug effects. J Med Chem 16(12):1324;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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