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Virginiamycin

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Definition: A cyclic polypeptide antibiotic complex from Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. It consists of 2 major components, VIRGINIAMYCIN FACTOR M1 and virginiamycin Factor S1. It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.     
Pharmacological Action Anti-Bacterial Agents; Protein Synthesis Inhibitors
Examples Streptogramin A 		Other names Staphylomycin; Virginiamycin Phibro Brand; Virginiamycin Hancroft Brand; Virgimycine; Stajac; SmithKline Beecham Brand of Virginiamycin; Phibro Brand of Virginiamycin; Hancroft Brand of Virginiamycin; Founderguard; Eskalin; Antibiotic 899
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
virginiamycin M2  0   Virginiamycin/*analogs & derivatives. Org Lett 2007 Aug 2;9(16):3105-8
VisD protein, Streptomyces virginiae  0   *Bacterial Proteins Virginiamycin/*analogs & derivatives. Gene 2002 Mar 20;286(2):283-90
VisC protein, Streptomyces virginiae  0   *Bacterial Proteins Virginiamycin/*analogs & derivatives. Gene 2002 Mar 20;286(2):283-90
VisB protein, Streptomyces virginiae  0   *Bacterial Proteins Virginiamycin/*analogs & derivatives. Gene 2002 Mar 20;286(2):283-90
VisA protein, Streptomyces virginiae  0   *Bacterial Proteins Virginiamycin/*analogs & derivatives. Gene 2002 Mar 20;286(2):283-90
virginiamycin factor S1  0   *Virginiamycin *Streptogramin Group B.
dalfopristin  112362-50-2   Virginiamycin/*analogs & derivatives.
Pharma Action Anti-Bacterial Agents 		J Chromatogr B Biomed Sci Appl 1998 Apr 24;708(1-2):161-8
quinupristin  120138-50-3   Virginiamycin/*analogs & derivatives.
Pharma Action Anti-Bacterial Agents 		J Chromatogr B Biomed Sci Appl 1998 Apr 24;708(1-2):161-8
RPR 106972  0   Virginiamycin. Antimicrob Agents Chemother 1996 Feb;40(2):481
13-deoxyvirginiamycin M1  118693-65-5 Virginiamycin M1, 14-deoxy  Virginiamycin/*analogs & derivatives. J Antibiot (Tokyo) 1991;44(6):613
13,14-anhydrovirginiamycin M1  119465-45-1 Virginiamycin M1, 14,15-didehydro-14-deoxy-, (14E)  Virginiamycin/*analogs & derivatives. J Antibiot (Tokyo) 1991;44(6):613
15-dihydro-13,14-anhydrovirginiamycin M1  118693-64-4   Virginiamycin/*analogs & derivatives. J Antibiot (Tokyo) 1991;44(6):613
quinupristin-dalfopristin  126602-89-9   *Virginiamycin.
Pharma Action Anti-Bacterial Agents ; Protein Synthesis Inhibitors 		Eur J Clin Microbiol Infect Dis 1989;8(12):1064SYNERCID
A2315A  58717-24-1 madumycin I, 15-deoxo-15-hydroxy-, (15S)  *Virginiamycin. J Antibiot (Tokyo) 30(3):197;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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