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Wegener Granulomatosis

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Definition: A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and kidneys. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against neutrophil proteinase-3 (WEGENER AUTOANTIGEN).     
See Also Myeloblastin; Vasculitis, Central Nervous System 		Other names Granulomatosis, Wegener's; Granulomatosis, Wegener; Wegener's Granulomatosis
 
SubstanceCAS Registry & nameCategoriesSource
Midline granulomatosis  0   *Wegener Granulomatosis.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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