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1-Sarcosine-8-Isoleucine Angiotensin II

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Definition: An ANGIOTENSIN II analog which acts as a highly specific inhibitor of ANGIOTENSIN TYPE 1 RECEPTOR.  DF: SAR ISO ANG   
Pharmacological Action Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents 		Other names 1-Sar-8-Ile Angiotensin II; Angiotensin II, 1-Sarcosine-8-Isoleucine; Angiotensin II, 1-Sar-8-Ile; 1 Sarcosine 8 Isoleucine Angiotensin II; 1 Sar 8 Ile Angiotensin II; Sarile; 1-(N-Methylglycine)-8-L-Isoleucine-Angiotensin II
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
angiotensin II, iodo-(Sar(1)-Ile(8))  0   1-Sarcosine-8-Isoleucine Angiotensin II/*analogs & derivatives Iodine Radioisotopes. Endocrinology 1996 Apr;137(4):1204-11
angiotensin II, Sar(1)-Val(5)-Ile(8)  51274-63-6   1-Sarcosine-8-Isoleucine Angiotensin II/*analogs & derivatives. J Med Chem 1991;34(8):2402
angiotensin II, Sar(1)-aza-Val(3)-Ile(8)  116370-31-1   1-Sarcosine-8-Isoleucine Angiotensin II/*analogs & derivatives. Acta Physiol Pharmacol Bulg 1988;14(1):22
angiotensin II, 1-Sar-7-Sar-8-Ile  68941-19-5   1-Sarcosine-8-Isoleucine Angiotensin II/*analogs & derivatives. Arch Biochem Biophys 1986;248(1):419
angiotensin II, 1-Sar-7-nipecotic acid-8-Ile  71381-74-3 Angiotensin II, 1-(N-methylglycine)-5-L-isoleucine-7-DL-3-piperidinecarboxylic acid-8-L-isoleucine  1-Sarcosine-8-Isoleucine Angiotensin II/*analogs & derivatives. Can J Physiol Pharmacol 57(7):763;1979
angiotensin II, 1-Sar-7-N-methyl-Ala-8-Ile  71381-73-2 Angiotensin II, 1-(N-methylglycine)-5-L-isoleucine-7-(N-methyl-L-alanine)-8-L-isoleucine  1-Sarcosine-8-Isoleucine Angiotensin II/*analogs & derivatives. Can J Physiol Pharmacol 57(7):763;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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