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17-Hydroxycorticosteroids

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Definition: A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal function. They are used systemically in the free alcohol form, but with esterification of the hydroxy groups, topical effectiveness is increased.     
Examples Cortisone; Cortodoxone; Hydrocortisone; Tetrahydrocortisol; Tetrahydrocortisone
Other names 17 Hydroxycorticosteroids
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Porter Silber chromogens  0   *17-Hydroxycorticosteroids Pigments, Biological. Arch Sci Physiol (Paris) 28(1):113;1974; Psychiatr Neurol Med Psychol (Leipz) 25(3):161;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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