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2-Isopropylmalate Synthase
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Definition
: An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12.
Other names
alpha Isopropylmalate Synthase; Synthase, alpha-
Isopropylmalate; Synthase, 2-
Isopropylmalate; 2 Isopropylmalate Synthase; alpha-
Isopropylmalate Synthase
Substance
CAS Registry & name
Categories
Source
Drugs
*
MAM3 protein, Arabidopsis
EC 2.3.3.13
*2-Isopropylmalate Synthase
*Arabidopsis Proteins.
Plant Physiol 2007 May;144(1):60-71
LEU4 protein, S cerevisiae
EC 2.3.3.13
*2-Isopropylmalate Synthase
*Saccharomyces cerevisiae Proteins.
Mol Microbiol 1993 Jan;7(2):215-28