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5,8,11,14-Eicosatetraynoic Acid

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Definition: A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F(2a).      Other names ETYA; Ro 3 1428; 5,8,11,14 Eicosatetraynoic Acid; Ro 3-1428; Ro 31428
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Triarachidonin  23314-57-0 5,8,11,14-Eicosatetraenoic acid, 1,2,3-propanetriyl ester, (all-Z)  5,8,11,14-Eicosatetraynoic Acid/*analogs & derivatives. Arch Biochem Biophys 1988;261(2):368
5,8,11,14-heneicosatetraynoic acid  19960-58-8   5,8,11,14-Eicosatetraynoic Acid/*analogs & derivatives. Prostaglandins 1981;21(2):323
4,7,10,13-eicosatetraynoic acid  77178-73-5 4,7,10,13-Eicosatetraynoic acid  5,8,11,14-Eicosatetraynoic Acid/*analogs & derivatives. Prostaglandins 1981;21(2):323

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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