Definition: A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Other names NSC-218321; Lederle Brand of Pentostatin; Deoxycoformycin; Co-Vidarabine; CI-825; 2'-Deoxycoformycin; NSC218321; NSC 218321; Co Vidarabine; CI825; CI 825; 2' Deoxycoformycin; Wyeth Brand of Pentostatin; Warner-Lambert Brand of Pentostatin; Supergen Brand of Pentostatin; Prasfarma Brand of Pentostatin; Nipent