Definition: A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent.
Other names 7-Ethoxycoumarin O-Deethylase; 7-Ethoxycoumarin O-Dealkylase; P-450-Dependent O-Dealkylase, Cytochrome; O-Depropylase, 7-Propoxycoumarin; O-Deethylase, 7-Ethoxycoumarin; Monooxygenase, 7-Ethoxycoumarin; Hydroxylase, 7-Ethoxycoumarin; Ethoxycoumarin O Deethylase; Deethylase, Ethoxycoumarin; Dealkylase, 7-Ethoxycoumarin; Cytochrome P 450 Dependent O Dealkylase; 7 Propoxycoumarin O Depropylase; 7 Ethoxycoumarin O Deethylase; 7 Ethoxycoumarin O Dealkylase; 7 Ethoxycoumarin O De Ethylase; 7 Ethoxycoumarin Monooxygenase; 7 Ethoxycoumarin Hydroxylase; 7 Ethoxycoumarin Dealkylase; 7 Alkoxycoumarin O Dealkylase; Ethoxycoumarin O-Deethylase