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Propofol

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Definition: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.     
Pharmacological Action Anesthetics, Intravenous; Hypnotics and Sedatives 		Other names Disoprofol; ICI35868; ICI35,868; ICI 35868; ICI 35,868; 2,6 Diisopropylphenol; Zeneca Brand of Propofol; Schering Brand of Propofol; Rovi Brand of Propofol; Recofol; Propofol-Lipuro; Propofol Rovi; Propofol MCT; Propofol Fresenius; Propofol Abbott; Pisa Brand of Propofol; Parnell Brand of Propofol; Juste Brand of Propofol; Ivofol; ICI-35868Drugs* : DIPRIVAN; PROPOFOL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,6-diisopropyl-4-(3-(3-methyl-3H-diazirin-3-yl)propyl)phenol  0   Diazomethane/*analogs & derivatives Propofol/*analogs & derivatives. J Med Chem. 2011 Dec 8;54(23):8124-35.
2,6-diisopropyl-4-(1-hydroxy-2,2,2-trifluoroethyl)phenol  0   Propofol/*analogs & derivatives. Anesth Analg 2011 Feb;112(2):340-4
m-azipropofol  0   Diazomethane/*analogs & derivatives Propofol/*analogs & derivatives. J Med Chem 2010 Aug 12;53(15):5667-75
fospropofol disodium  258516-87-9   Propofol/*analogs & derivatives.
Pharma Action Hypnotics and Sedatives 		Eur J Anaesthesiol 2003 Mar;20(3):182-90LUSEDRA
nitrosopropofol  0   Propofol/*analogs & derivatives. Biochem Pharmacol 2002 Oct 1;64(7):1133-8
4-iodopropofol  0   Propofol/*analogs & derivatives. Anesthesiology 2001 Jun;94(6):1050-7
4-iodo-2,6-diisopropylphenol  0   Propofol/*analogs & derivatives. J Med Chem 1998 May 21;41(11):1846-54
propofol hydroxypropyl-beta-cyclodextrin  0   *Propofol *beta-Cyclodextrins. Arzneimittelforschung 1993 Aug;43(8):818-21

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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