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Eukaryotic Initiation Factor-2

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Definition: Eukaryotic initiation factor of protein synthesis. In higher eukaryotes the factor consists of three subunits: alpha, beta, and gamma. As initiation proceeds, eIF-2 forms a ternary complex with Met-tRNAi and GTP.      Other names Peptide Initiation Factor EIF-2; EIF-2; Peptide Initiation Factor EIF 2; Initiation Factor-2, Eukaryotic; Eukaryotic Peptide Initiation Factor 2; Eukaryotic Initiation Factor 2, gamma Subunit; Eukaryotic Initiation Factor 2, beta Subunit; Eukaryotic Initiation Factor 2, alpha Subunit; Eukaryotic Initiation Factor 2; EIF 2gamma; EIF 2beta; EIF 2alpha; EIF 2 gamma; EIF 2 beta; EIF 2 alpha; Eukaryotic Peptide Initiation Factor-2; EIF 2; Eukaryotic Initiation Factor-2, gamma Subunit; Eukaryotic Initiation Factor-2, beta Subunit; Eukaryotic Initiation Factor-2, alpha Subunit
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
eukaryotic initiation factor-2 alpha, Toxoplasma gondii  0   *Eukaryotic Initiation Factor-2. Biochem J 2004 Jun 1;380(Pt 2):523-31
FUN12 protein, S cerevisiae  0   *Eukaryotic Initiation Factor-2 *Saccharomyces cerevisiae Proteins.
Rps16 protein, human  0   *Ribosomal Proteins Eukaryotic Initiation Factor-2. Blood 2001 Jan 15;97(2):579-80
Gerp95 protein, rat  0   *Membrane Proteins *Eukaryotic Initiation Factor-2. Mol Biol Cell 1999 Oct;10(10):3357-72
eIF-2 Met-tRNA(f)(met) GDPCP  0   *RNA, Transfer, Amino Acyl *Eukaryotic Initiation Factor-2. FEBS Lett 1980;113(1):125

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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