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Factor XIa

More information in Books or onNLM PubMed
Definition: Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium.  /defic   
See Also Coagulants 		Other names Activated Factor XI; Factor XI, Activated; Coagulation Factor XIa; XIa, Coagulation Factor; Factor XIa, Coagulation; Contact Activation Product; Blood Coagulation Factor XI, Activated
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
clavatadine A  0   *Guanidines *Phenylacetates Factor XIa/antagonists & inhibitors. 3583-7J Med Chem 2008 Jun 26;51(12):

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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