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Methacholine Chloride

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Definition: A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)     
Pharmacological Action Bronchoconstrictor Agents; Muscarinic Agonists; Parasympathomimetics; Miotics
Other names Methacholine; Chloride, Methacholine; Acetyl beta methylcholine; Acetyl beta methacholine Chloride; Acetyl 2 methylcholine Chloride; Roche Brand of Methacholine Chloride; Provokit; Provocholine; Methapharma Brand of Methacholine Chloride; Mecholyl; Mecholine; Lindopharm Brand of Methacholine Chloride; Acetyl-beta-methylcholine; Acetyl-beta-methacholine Chloride; Acetyl-2-methylcholine Chloride; 2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium ChloDrugs* : PROVOCHOLINE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
esmodil  0   Methacholine Chloride/*analogs & derivatives. Nat Prod Res 2004 Aug;18(4):305-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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