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Endothelial Growth Factors

More information in Books or onNLM PubMed
Definition: These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.  do not confuse with EGF; (EPIDERMAL GROWTH FACTOR)   
Pharmacological Action Growth Substances
See Also Vascular Endothelial Growth Factor A 		Other names Growth Factor, Endothelial; Endothelial Cell Derived Growth Factors; Endothelial Growth Factor Polypeptides; Endothelial Growth Factor; Endo-GF; ECDGF; beta-Endothelial Growth Factor; alpha-Endothelial Growth Factor; Endothelial Cell-Derived Growth Factors; beta Endothelial Growth Factor; alpha Endothelial Growth Factor; Growth Factors, Endothelial; Growth Factor, beta-Endothelial; Growth Factor, alpha-Endothelial
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
EGFL8 protein, human  0   *Endothelial Growth Factors. Anticancer Res 2011 Jun;31(6):2249-54
EGFL7 protein, human  0   *Endothelial Growth Factors. EMBO J 2003 Nov 3;22(21):5700-11
cyclo-VEGI  0   *Peptides, Cyclic *Endothelial Growth Factors. J Biol Chem 2003 Sep 12;278(37):35564-73

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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