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Iloprost

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Definition: An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.     
Pharmacological Action Platelet Aggregation Inhibitors; Vasodilator Agents 		Other names Ciloprost; ZK36374; ZK 36374; ZK-36374; Ventavis; CoTherix Brand of IloprostDrugs* : VENTAVIS
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
eptaloprost  90693-76-8   Iloprost/*analogs & derivatives. Adv Prostaglandin Thromboxane Leukotriene Res 1991;21B:901
2,6-dichloro-4-aminophenol iloprost  124578-04-7   Iloprost/*analogs & derivatives. Biochem Biophys Acta 1989;993(1):74
iloprost phenacyl ester  122405-30-5   Iloprost/*analogs & derivatives. Curr Eye Res 1989;8(2):131

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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