Definition: Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
Other names Trans-Acting Responsive Region, HIV; Sp1-Binding Site, HIV; Negative Regulatory Element, HIV; Long Terminal Repeat, HIV; Human Immunodeficiency Virus Long Terminal Repeat; HIV Trans-Acting Responsive Region; HIV Sp1-Binding Site; HIV Negative Regulatory Element; Trans Activation Responsive Region, HIV; Trans Activation Responsive Element, HIV; Trans Acting Responsive Region, HIV; TAR Elements, HIV; Sp1-Binding Sites, HIV; Sp1 Binding Site, HIV; LTR, HIV-1; HIV Trans Acting Responsive Region; HIV TAR Elements; HIV TAR Element; HIV Sp1-Binding Sites; HIV Sp1 Binding Site
